Llama 3.1 405B Instruct vs Mistral Large 2 (2407): the real cost to run each

The honest, $0-markup cost to run Llama 3.1 405B Instruct (Meta, 405B) and Mistral Large 2 (2407) (Mistral AI, 123B), side by side — free on your own machine, on your own rented GPU at the vendor's price, or via your own API key.

Llama 3.1 405B Instruct vs Mistral Large 2 (2407) — cost comparison

Llama 3.1 405B InstructMistral Large 2 (2407)
Parameters405B123B
Context window131.1K131.1K
LicenseCommercial OKRestricted
VRAM to run~290 GB (Q4_K_M)~92 GB (Q4_K_M)
Rent a GPU$3.43/hr$1.30/hr
Your API key$0.80/1M (last-known)$1.08/1M (est.)

Which should you pick?

VRAM, size, context and license are facts from the catalog and the shared cost engine; API prices are real where we have them (labeled "est." otherwise). We don't rank model quality or quote benchmarks here.

Full cost breakdown: Llama 3.1 405B Instruct →
Full cost breakdown: Mistral Large 2 (2407) →

Open the free Spanvero advisor → to compare them live for your exact workload and hardware.

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Spanvero · All comparisons · Prices as of 2026-06-17. $0 markup, your own accounts, we never resell compute. © 2026 Cynosure LLC.