Llama 3.1 405B Instruct vs Qwen3-235B-A22B: the real cost to run each

The honest, $0-markup cost to run Llama 3.1 405B Instruct (Meta, 405B) and Qwen3-235B-A22B (Alibaba, 235B), side by side — free on your own machine, on your own rented GPU at the vendor's price, or via your own API key.

Llama 3.1 405B Instruct vs Qwen3-235B-A22B — cost comparison

Llama 3.1 405B InstructQwen3-235B-A22B
Parameters405B235B
Context window131.1K41K
LicenseCommercial OKCommercial OK
VRAM to run~290 GB (Q4_K_M)~160 GB (Q4_K_M)
Rent a GPU$3.43/hr$1.96/hr
Your API key$0.80/1M (last-known)$1.14/1M

Which should you pick?

VRAM, size, context and license are facts from the catalog and the shared cost engine; API prices are real where we have them (labeled "est." otherwise). We don't rank model quality or quote benchmarks here.

Full cost breakdown: Llama 3.1 405B Instruct →
Full cost breakdown: Qwen3-235B-A22B →

Open the free Spanvero advisor → to compare them live for your exact workload and hardware.

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Spanvero · All comparisons · Prices as of 2026-06-17. $0 markup, your own accounts, we never resell compute. © 2026 Cynosure LLC.