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gpt-oss-20b vs Mixtral 8x7B Instruct: the real cost to run each

The honest, $0-markup cost to run gpt-oss-20b (OpenAI, 21B) and Mixtral 8x7B Instruct (Mistral AI, 46.7B), side by side — free on your own machine, on your own rented GPU at the vendor's price, or via your own API key.

gpt-oss-20b vs Mixtral 8x7B Instruct — cost comparison

gpt-oss-20bMixtral 8x7B Instruct
Parameters21B46.7B
Context window✓ 131.1K32.8K
LicenseCommercial OKCommercial OK
VRAM to run✓ ~15 GB (Q4_K_M)~34 GB (Q4_K_M)
Rent a GPU✓ $0.12/hr$0.24/hr
Your API key✓ $0.08/1M$0.24/1M (last-known)

Which should you pick?

VRAM, size, context and license are facts from the catalog and the shared cost engine; API prices are real where we have them (labeled "est." otherwise). We don't rank model quality or quote benchmarks here.

Full cost breakdown: gpt-oss-20b →
Full cost breakdown: Mixtral 8x7B Instruct →

Open the free Spanvero advisor → to compare them live for your exact workload and hardware.

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Spanvero · All comparisons · Prices as of 2026-07-06. $0 markup, your own accounts, we never resell compute. © 2026 Cynosure LLC.

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